Current progress in pharmacogenetics
نویسندگان
چکیده
منابع مشابه
Genetics and Pharmacogenetics of Schizophrenia: Recent Progress
Schizophrenia is a complex and debilitating chronic mental illness, and genetic factors play a major role in its etiology and development. Traditional genetic studies estimated the heritability of schizophrenia to be 70% to 90%.1 With the rapid advance of genomic technologies, the past decade has seen an explosion of genetic studies in schizophrenia, which opened new doors for our understanding...
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The treatment of medical conditions with cannabis and cannabinoid compounds is advancing. Although there are numerous reports related to the genetic variations of the cannabinoid receptor, a lack of studies that examine the relationship between other pharmacogenetic markers and health outcomes currently exists. Herein, we advocate for the legalization of marijuana in the United States in order ...
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The content covers congenital, developmental and degenerative conditions, trauma, growth and infection related disorders, and clinically relevant basic scientific research. Congenital abnormalities affecting the limbs remains a great challenge to orthopaedic surgeons, but development in this field is swinging from amputation and prosthetic fitting to bone and soft tissue reconstruction due to b...
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INTRODUCTION Antipsychotic drug is the mainstay of treatment for schizophrenia, and there are large inter-individual differences in clinical response and side effects. Pharmacogenetics provides a valuable tool to fulfill the promise of personalized medicine by tailoring treatment based on one's genetic markers. AREAS COVERED This article reviews the recent progress in pharmacogenetic research...
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"Personalized medicine” represents a conceptual change in pharmacotherapeutics, where an individual's genetic profile will determine the appropriate drug and/or dose the patient should receive. Currently, medicine is addressing this challenge through the lens of genomic technologies. In the domain of anthithrombotic therapy, warfarin, clopidogrel and aspirin are still the most relevant drugs fo...
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ژورنال
عنوان ژورنال: British Journal of Clinical Pharmacology
سال: 2011
ISSN: 0306-5251
DOI: 10.1111/j.1365-2125.2011.03912.x